Advice and support to achieve confident results

You need a solution you know you can trust and that will justify your investment. SurgVision can advise and support you in securing those assurances. of your imaging.

You need confidence that the technology supports reaching your goals with results that stand up under scrutiny. You need

  • reassurance that you can rely on the in vivo results.
  • trust that the fluorescence imaging matches current ex vivo procedures.

SurgVision can help you co-localize the fluorescence imaging results with the target tissue. That is, we support your work with the SurgVision platform technology to help get results you can rely on. Our expertise originates from work at the Technical University Munich, and continual work to meet the practical needs of clinical studies (such as at the University Medical Center Groningen, University Medical Center Utrecht, Martini Hospital, Groningen. Moffitt Cancer Center, Tampa, Florida, and Stanford University, California).

In short, we can help you ensure what you see in vivo using the SurgVision platform technology matches the gold standard of histopathology.

7 Images from Harlaar N.J., Koller, M et al. Molecular Fluorescence Guided Surgery of Peritoneal Carcinomatosis of Colorectal Origin – A Paradigm Shift . Lancet Gastroenterology & Hepatology. 2016 vol. nn no. n ppp-ppp. 8 FFPE = Formalin-fixed, paraffin-embedded

Procedural expertise for your ease of application

From the beginning, we developed the SurgVision platform technology with validation in mind. Our adaptable multiplex advanced pathology imaging (MAPI) technology provides a qualitative way of co-localizing tracer with other biomarkers. Depending on the needs of your validation, we can help you define a process that can correlate macroscopic, mesoscopic and microscopic imaging of tissue and tissue slices from your excised specimens.

These images shows confirmation of the colocalization of fluorescence with pathology results.

a) In vivo white-light imaging

b) Overlay of the in vivo white light and near infrared fluorescence (NIRF) images

c) Ex vivo white-light imaging

d) Fluorescence flatbed (ex vivo) scanning

e) Fluorescence flatbed scanning of the 10 μm slide

f) Hematoxylin&eosin staining of the 10 μm slide, and

g) VEGF immunohistochemistry

Using the configuration flexibility of the SurgVision platform technology, we have customized a "black box" version for ex vivo imaging in or near the OR, to bridge the gap between image-guided in vivo assessment and image-guided pathology.

Procedural expertise for your ease of application

Trust what the camera system shows you: that is why we developed the SurgVision Calibration Disk. You can prepare tubes with a scattering agent and different concentrations of your tracer. By imaging the disk before and after the procedure, and by rotating the disk through the field of view, you can be sure that what you are seeing is validated, homogenous and repeatable.

The calibration disk also opens the possibility of correlating results from the SurgVision Explorer Air with your other equipment. This can increase confidence in the consistency of your interpretations through different stages of your tracer development.